Synthesis of Some New Substituted Isatin Derivatives with Possible Antipyretic Activity
Substituted isatin derivative have been prepared by treating substituted aromatic amines with hydroxylamine hydrochloride with chloralhydrate in presence of sodium sulphate to form 2-hydoxyimino-N-p-tolyacetamide which on reaction with conc. H2SO4 to give 5-s…